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I was given this advice from the design engineer of a well known Audiophile Power Conditioner manufacturer."Use round Romex 10/3 or 12/3. Inside are 4 wires, a black, white, red and bare wire(s). Use black for hot, white for neutral, the red and the bare are both for ground (using 2 wires for ground gives you a much lower impedance path to earth ground resulting in a quieter system with a lower noise floor).
If you need two circuits, you'd need 10/4 or you'd have to run a separate ground.The isolated ground by itself is really not useful unless you combine it with a metal box and metal conduit and metal cover. Then, the body of the outlet is connected to the metal of the cover and the metal of the box (and to the isolated ground), and there's an entire grounded "shield" around the wires and the outlet. Without that grounded "shield", the isolated ground isn't useful. And this only prevents/reduces electromagnetic coupling into the wires; any "garbage" that's on the wires to begin with isn't effected.
I've read a number of posts here at the AC on this very subject, and to me, most guys go way overboard.Sure it's nice to have a couple of dedicated lines, but hooking amps to one branch and preamps and other stuffto another branch, asks for trouble. Good grounding (to eliminate possible hum issues) involves a single point,not spread over several branch circuits. If you have 3 prong grounded equipment, this may lead to problems.
I have two 20A dedicated circuits on the same phase. Zero hum, zero issues. I have amps plugged into one duplex outlet and everything else plugged into another. Now, both my 20A dedicated circuit wires run in the same conduit and are within probably an inch of being the same length, which may not be true for anyone else. I do have hum in a sub on a different circuit, but I've been able to alleviate that, and the sub is across the room, so it has to be on a different circuit.
It's not hard to have the 2 circuits in phase as the 240 volt service to your house is single phase.