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Or if you really want to have some fun, redesign the input stage to use a 5842, or if you're somewhat insane, the 6C45P. Much different sound from the typical audio tubes, much faster, much more wide-band, and more dynamic.
A few things. The plate impedance of a 12AX7 or 6AV6 is somewhere in the region of 70-80k ohms, and the plate resistor is only 100k which is far too low. Tubes like to see a plate resistor of around 4-6 times their plate impedance in order to run with minimal distortion, however this isn't really possible with a 12AX7 unless a CCS is used. As is, the 12AX7 or 6AV6 is going to distort, a lot. Also, a given that a 45 is biased around 50V or so and typical sources these days put out a healthy 2V or so, the high gain from the 12AX7 or 6AV6 is mostly wasted since all it does is overload the output stage, and with RC coupling the overload recovery is slow and ugly. A 12AT7 or 12AY7 will give you enough gain, along with the bonus of having a much lower plate impedance so that they'll actually run fairly distortion free with a 100k plate load. You could even drop the plate resistor to around 65-80k with the 'AT & AY7, respectively.Or if you really want to have some fun, redesign the input stage to use a 5842, or if you're somewhat insane, the 6C45P. Much different sound from the typical audio tubes, much faster, much more wide-band, and more dynamic.
But it has no current output so its going to roll off from the miller C of the following tube. The 45 doesn't have a great deal of miller C but it has some. Then since this is cap coupled and there is no Ip to speak of you are going to run into blocking distortion, since you don't have the I to charge up the capacitance quickly enough. I think this is why there is a huge multitude of designs out there that try other means of getting there.I read some experience from a few experienced DIY'ers such as SY who claim that the 12ax7 *can* have good linearity and distortion figures but that it is *extremely* finicky and hard to actually obtain in a real circuit.
Actually, the design values were taken directly from Philips' published data dated January 1970. According to said data, the ECC83 (aka 12AX7) will have a gain of 57 v/v, have a maximum output of 30 VRMS (which is around 85 p-p) at 2.7% distortion maximum... all based on the operating parameters per the schematic I posted. If this was a big problem I think someone would have found it before now.