the NX-Otica (non mtm version) is only about 75 lbs built so they really aren't overly heavy to move around.
In a small/medium room such as mine (18x12), the NX-Otica's do very well on their own with no subs. I posted some RtA graphs of in room response I was getting (I'll see if I can dig up the thread), Ron Breny of NRD jumped in and posted similar results with his NX-Otica's in a similar sized room.
Here it is, this graph was using a little low end boost below 40hz in Roon's Parametric EQ ( no subs)
Here's the thread if you want to see a bit morehttps://www.audiocircle.com/index.php?topic=158550.msg1697216#msg1697216
When we compared the NX-Otica's & dual H-frames to the NX mtm's & dual h-frames, we always preferred the NX-Oticas. The better integration with the subs and additional punch in the 100-200 hz range from the additional 4 M165(X)'s per side was very noticable. Having those extra 4 woofers per channel also eliminates teh low end workload from the 2 M165NQ midrange drivers on each side and leaves them to focus solely on the midrange.
Yes, withthe full Otica's you have to high pass the M165NQ's with a large bundle of caps butwe didn't notice any loss of detail in the midrange.
The Mtm's are great if you don't have the space and definately want the subs but, if you have the room or are in a smaller room and don't mind going subless, my personal recommendation would be the full NX-Otica's.