There are good descriptions in the threads Delacroix linked to on how this should or can be done.
What I mostly did when biamping with a class D 400w into 4 ohm on the bass-cabinets of VR4Jr and VR4genIII,was to use different integrated tubeamps on the mid/tweeter.That way I could tailor in the overall balance I wanted with the volumecontrol on the tubeintegrated. For me much of the fun-part was having the ability to adjust that balance a little bit from day to day,if me ears are tired I usually prefer a warmer balance if I want to listen to music,when ears are fresh I might like things more upfront.And that also give the nice opportunity that you can tailor it to recordings as well.
The best result I think is when you have "the best" poweramp on the top,one without volumecontrol,and then a higher gain amplifier on the bass with volumecontrol.If you find out that you like one setting of the volumecontrol only,then all volumecontrols can be measured in that prefered position and be replaced by very high quality resistors to get the most transparency.