I would say in 99% of the cases, no. An interconnect is made up of a much smaller gauge wire than speaker cables, which wouldn't be sufficient enough to handle the greater current a speaker cable would see. This would be a fire hazard.
Further, typical interconnects are made differently than speaker cables. They usually are a single conductor with a braided shield. The conductor is the positive connection and the braid is the negative. On the other hand, a speaker cable is usually 2 conductors (or multiple conductors), with one conductor(s) going to the positive and the other conductor(s) going to the negative.
By the way, welcome to AC!

Paul