Speaking as a formerly sighted, and now totally blind audiophile, I can say that it does make a difference.
A little explanation is in order though. True enough just about anything I do, whether it be travelling down the street or across continents, building things -- wood electronics, etc. -- is usually perceived by those around me to be some sort of supernatural talent, and same goes for listening to audio gear. People just assume that as I'm blind I again must have supernatural hearing. I don't. What I do have is over 18 years of experience in relying on my ears to fill in the missing visual information, which translates into paying much closer attention to things, but with a much higher percentage happening at the subconcious level as compared to a normal person.
Yeah, what's normal? A setting on a dryer. But it gets the point across.
So, back to the normal person -- he/she typically uses about 94% - 98% of his conscious cognitive bandwidth processing visual information, and hearing, haptics (touch), and olfactory inputs occupy the rest. This of course varies greatly from person to person, and about a zillion other factors, so just take as a generalized concept.
When I sit in front of my stereo, I'm not having to deal with any visual input taking a slice out of that cognitive bandwidth, so naturally more of it is given to auditory processing. Now, it's not like I just invert the ratios and use 9x% on auditory, because there is still mental imagery going on, as well as that subconscious correlator that is processing peripheral information -- is somebody coming into the room?
The point of all this is that I certainly have noticed in my years as a blind person, I hear things that others don't -- whether that be in day to day life or in front of an audio system. Please note that this is not the same as saying that I hear better -- it means I just may be more subconsciously taking in more details, and of course, a trained audiophile/listener, whatever you want to call yourselves, can do the samme, but it usually takes a very specific set of cognitive and environmental conditions -- mood attention span, dim lighting, etc.
Many years ago Bud Purvine did some listening tests with off-the-street type listeners of all backgrounds, and also had some blind subjects take part, and to a person, the blind listeners heard the difference that none of the other Joe Pedestrians did. He'd be the one to ask about specifics though.
Hope this all made some sort of sense -- it's a little hard to squeeze enough cognitive neuropsychology into a short reply

-- Jim