Just one? It's not possible. I've recently been trying to find the best selection. this is what I've come up with so far...
Tom Petty and the Heartbreakers, "Running Down a Dream" (now, there's a simple but just perfectly executed guitar solo. I love it!)
Chicago, "Twenty-five or -six to four"
Ten Years After, "I'm Going Home"
Cream, "Sunshine of your Love", "White Room"
Derek and the Dominoes, "Why Does Love Got To Be So Sad"
Bonnie and Delaney w/ E.C., "Coming Home"
The Beatles, "Hey Jude"
Hendrix, "Long Hot Summer Night", "Voodoo Chile", "All Along the Watchtower"
Rolling Stones, "Sympathy for the Devil", "Paint it Black", "Gimme Shelter"
The Police, "Message in a Bottle", "Synchronicity II"
Chad