I'll take a crack as this one, I'm up late anyway, if you're designing away right now don't get too far. For a 6.76 cu. ft enclosure, 4 4" diameter ports would have to be much longer to tune to 33hz, somewhere around 15.5 inches long I think(quick calculator on my iPhone) so not 100% sure, but they would have to be much longer. It's not just the total port opening area, it's each ports opening area in relation to length, tuned to the enclusure volume, per number of ports. Larger diameter ports need to be longer to tune the same as smaller ports. The amount of ports can also change tuning vs. total port area by lenght.
I think there's also something to be gained in low end extension by aranging the woofers in a long line. A square box might not go as low. Admitedly I've had a couple beers so I could be off on that, but not too far

Should still make a quick punchy sub. If they're suitable drivers, you could make a few 1/4 horns or tapped horns, although it gets much more complicated...long story short, the design would work, but you may lose a little extension, and you'll need longer ports.