I started using powerline networking in my home a couple of years ago.
Life before installing powerline networking with regards to my audio system:
- Audio system runs completely on dedicated AC lines
- All components use some kind of AC filtering product (mostly Audience adeptResponse)
- Music source was Logitech Transporter used as transport to feed a DAC (Dodson Audio). Transporter was being used in wireless mode.
I installed powerline networking in my home because my wi-fi network was not reaching all corners of my house that I would like (ie. could not get a reliable wi-fi signal in my bedroom). The initial install only included using it with my computers. I did not notice any effect on the sound quality of my audio system.
Later, I decided to see what would happen if I connected my Transporter to the powerline network (instead of using Wi-Fi). There is an AC outlet near my audio system that is not its own dedicated line, so I used that one to connect to my Transporter's ethernet port. The result was a noticeable improvement in sound.
So from my experience, powerline networking did not have a negative impact on my system's performance, and in fact bettered the performance as it related to my music server.
Just my two cents...