Its a small upgrade...probably similar to upgrading binding posts or inductors. If you're going all-out, its a worthwhile investment, but if you're not sitting back and picking out every detail...maybe not worthwhile.
I went and upgraded binding posts, caps n resistors, inductors, wire, and used no-rez on my pair of N2X...mostly because I saved so much by using PE cabinets and there's not a lot of wire, either. Couldn't imagine the cost of this wire on a pair of Line Source speakers.