I've never heard of the H2O amplifier. Reading the positive feedback review, it sounds like they could be describing the Wyred amp. A few things in the review stood out to me:
"Instruments stood crisply at attention, though they lacked the body that my tube amps provide", "The H2O lacked the warmth and inner light that characterizes the best tube gear", "deeper voice like Joe Williams' was missing the slow warmth it has with my tube amps", "Female voices sounded a bit more forward than usual", "In the treble region, the H2O had detail like that of solid-state gear that costs many times as much, though it lacked the inner light, and the warmth and emotional involvement, of the best tube gear"
While auditioning this amp would be the only way to know how it sounds in my system for sure, these comments tend to make it sound like I would be getting into the exact same thing as the Wyred amp. I don't want to end up substituting detail for emotional involvement.