Thanks Bryan.
To be clear, the higher side is the one that opens to the rest of the house. It continues up to the ridge beam that runs the entire length of the living spaces. As a result, there is no wall/ceiling edge there to treat. (There is another ridge beam through the proposed listening area that could be treated that way, however.)
Basically, the right side toward the front wall is completely open to a smallish dining room, whose own ceiling is nothing more than the floor of a loft type area above, which is turn open to the vaulted roof of the home above it. To the right hand side, further back toward the listening position, are the stairs to that loft (and the two guest bedrooms).
Clear as mud, I know...
Of course, a general answer to this type of question is all I was really looking for in the first place. I've seen it in enough other homes that I figure some type of approach must be known.