Other than very small horns or computer speakers, almost any speaker sounds better in large rooms. OBs can work just fine in any room with virtually any placement, because, unlike box speakers, they are completely and easily tuneable. I've even used them nearfield at a desk facing up against the wall with one edge of the baffle against the wall in only a 7'x10' space, and they sounded much better than boxes in the same room. Most of the old console stereos were OBs using heavy rearwave attenuation in an open backed box with placement right at the wall. OBs are only limited in use by your imagination, and they can specifically outshine boxes in small rooms, since they always add a greater sense of space.