I was having trouble consistently getting a good wireless signal to my sqeezebox, so I wired it. The setup is Internet "modem" to Netgear WRT54GS router (third party firmware) wire connection to Netgear switch to which my main computer (where the music files are located) and Squeezebox are hard wired out of.
I have no problem listening to my flac files from the main computer on the squeezebox, or accessing the internet on the computer. The computer is running Win2k, IE6, and fully updated.
If it matters the network cable to the squeezebox is pretty long-maybe 40 or 50 feet.
I didn't do anything special to the squeezebox when I switched to wired, just hooked in the network cable and fired up slimserver on the computer.