The FRYKLEANER is not designed for directional cables. The outputs are the same, with one set inverted. When a cable is looped, there is no voltage across the cable, only ac current. Current flows in both directions. Basically, both ends of the cable see a "source".
The FRY PRO is a little different, in that the top RCA (or binding post) is hot, the bottom is a short to ground (receiver). So the top RCA is driven with both polarities, the bottom center pin is ground, shield open. Thus, it does both voltage can current mode burns at the same time. The center conductor gets current, but the shield has a voltage and exercises the dielectric. This hookup method does not drive current through shield, but it seems to be very effective.
The new FRY GOLD is different still. I decided I didn't want to make that compromise, but instead force the user to run two separate modes. Rather than doing both at once, I specify to run voltage mode first, by only connecting to the top RCA. After a time, then connect to the bottom RCA. This then drives current through both center conductor and shield.
They all get the job done. The FRY PRO is just a little more convenient.
Anyway, to answer your question, I would run it in voltage mode for awhile by only connecting to one RCA. Then do a current mode by shorting both conductors at the far end to ground.
jh