Hi Russ,
Yes there are issues.
You would do best to use the lowest impedance network that will not load your previous stage. Say it's 10K then use a 11K in parallel with the input 100K and a C that gives the corner frequency you want. The impedance at the input will be raised considerably (~ 5K) at the corner frequency and it will pick up stray hum and supply radiated hash accordingly to the raised input impedance, compared with being connected directly to a low impedance source. As the impedance of the C falls so to does the impedance at the input and the pickup.
In reality you want a good quality C at the input that will not smear the sound , maybe a 1uF WIMA polypropylene so set your R to corner with that.
Cheers,
Greg