Hi Andy,
Yes, I was talking about powered subs.
Most subs have both low (line-level) and high (speaker-level) inputs. The latter tend to sound better - the sub is getting the same signal as your main speakers. Even though you're running this from your amp, it's no power drain on the amp - it's just using the signal to drive its internal amp. It may be just related to phase (and thus could be adjusted out), but as I said, the low-level inputs usually sound a bit disconnected from the music, many find.
As for driving the sub via low-level, I was talking about the *no preamp* case ("source" here means the digital source, specifically *not* a preamp). If you have an active preamp, no sweat at all - any such unit certainly has the current reserves to drive two ouputs, including long interconnects. With a passive linestage or no linestage at all, it's a different story. Some people will do this (2 amps, long ICs) with TVCs, which of course convert extra gain (voltage) to current and thus have better drive capabilities than resistor-based passives, but again a resistor passive or source-direct is different.
The problem is that dynamics can suffer because the source must provide all current needed to drive the amp(s). With a Y-connector off the source, driving two amps, one of them probably with long ICs, I think dynamics are bound to suffer - probably seriously - as the current-delivery capabilities of almost any source is going to be seriously taxed.
So, if you're using a resistor-based passive, or source-direct, really try to avoid driving two amps (such as a sub) and long ICs as well. This is the common wisdom. I have found it to hold true with passive (resistor) linestages.