The Audiophile 192 would send a digital stream to my DAC, the Revolution 5.1 digital would be sent to my Pre/Pro.
All of my audio experience has been non PC related but my experience has been that devises that do all things master none. DVD-A/SA-CD players would be a good example. I have never found that did justice to Redbook PCM. It's my reasoning for two sound cards. The 5.1 card will not do 2 channel stereo as well as the dedicated stereo card will.
If it helps, the digital stream coming off of any sound card, assuming the clock is good, will be identical. If you have reason to believe the 2 channel card has a better clock than the 5.1 channel card, it might be worth it. I dunno, though. I'd ask the card manufacturer if they use the same clock internally.
Assuming there are no glitches in running two sound cards, what you'll probably find is that one of them becomes the default card, and all your music applications will use that one, because they've all been written to assume a system has only one card, so the default one must be it. Smart apps will realise there are two and let you pick one, but...
If you don't get any other answers here, I'd definitely have a chat with the folk who provided your software, and the card manufacturer/vendor. This has the feel of something that will work, but only after much pain.