The modern trends are active speakers with controlled directivity and multiple subwoofers, pretty much the opposite of what you have in mind.
Active speakers are nearly always 2 or 3 way monitors with built-in power amps. Active means that they're fed a low voltage analog signal (RCA/XLR) or digital signal to a sophisticated crossover which then feeds individual channels of amplification, one channel per driver. Technical and sonic performance stomps audiophile traditional passives. There is no need for a bank of drivers. And imaging is greatly improved.
Controlled directivity addresses the disconnect between woofer and tweeter dispersion for again, enhanced imaging at the crossover frequency and provides the same performance regardless of the room. It usually involves use of a waveguide, which looks like a horn loading of the tweeter, but can also employ helper woofers with advanced circuitry to develop a cardioid shaped bass dispersion pattern.
Suggest reading Floyd Toole's "Sound Reproduction" the consummate audiophile guide to learning how speakers/subwoofers behave in-room. Room inevitably have bass peaks/dips, up to 30 dB! 3 or 4 carefully placed subwoofers help smooth out those peaks/dips. Proper absorption treatments can also help (contact GIK here at Audio Circle). Note that two full range speakers typically cannot be in the ideal location to generate bass and midrange/treble.
Feel free to reply here or PM me for more advice.
