If you "need" to boost input because of too low input signal then you're not close to digital clipping inside the DCX. That's OK to do, that's why they are there, to get a strong signal to noise ratio before going into DSP section. Raise it as much as you need to achieve the levels you want. Just avoid lighting the "clip" lights on the input and output level meters during playback and you're fine.
The sub output level can be a different than the other outputs, that's OK. This is the nature of any active speaker crossover, different drivers will have different sensitivity, and the DCX can compensate for this and make them play well together.
Some tube preamps can put out 20V, so that would be too much for the DCX and would trigger the input clip light and sound distorted. SS preamps might make 2-5V or more. DCX, being a pro audio tool should have no problem handling a consumer signal level. Just use common sense and avoid the dreaded clip lights and it will all work out fine.
The clip lights merely indicate when the headroom in DSP for the signal level has been exceeded. This digital clipping sounds horrible so it's not hard to avoid it.
