Jcoat,
How much do you want to spend? Jena Ultrawire is as good as it gets for hookup wire. Ultra-pure copper, cryogenically treated, and a very good insulation with that is equivalent to teflon in sound quality, but much easier to work with. However it costs $4', which might be overkill for some projects.
I've used it in all of my recent projects, and love the sound. Very detailed, musical, and with no loss in the frequency extremes.
And hey, what do you know... now I sell it. So take my message with a grain of salt
Cheers,
Kevin Whilden
Solar Hifi