The Dual Core has been the by far, the single biggest upgrade I've ever made in 4 decades. And it's not about what it is designed for, room correction, but on the fly user configurable adjustments to tame bad recordings or late night listening (loudness control) that has been missing since our audio gear (my Yamaha CR820) which had tone controls as well as a loudness control. Of course those tone controls degraded music although I don't remember having a problem with that in my youth.
I have a good room. Bass integration wasn't a problem. Of course my wife being an audio girl, doesn't mind the bass traps and acoustic panels layered around the room. Regardless, the anti-mode seems to mitigate to an extent, room deficiencies.
But that doesn't mean one can have a bad room and the Anti-Mode will fix it. It's built to work under 500Hz and as Danny mentioned (I think) better at up to 200Hz although I found that playing around with various frequencies up to 500HZ
might benefit some bad room interactions YMMV. One should apply standard practices where one can.
There isn't really any single configuration. One could play with an infinite amount of settings and save them in a profle which is also on the fly changeable. The documentation is lacking - severely. It outlines many setups but for instance, I've employed 4 subs the other day on a pair of high quality monitors that woof with a Scanspeak 4.5" driver. It will tune to 4 subs but seemingly only using the anti-mode for subs. I use the anti-mode for my preamp! My current setup is having daisy-chained 2 Atom subs with 2 Def Tech HT speakers with built-in subs at the rear, just using the built-in subs. There's really no instruction for how to do that. So I "pretended to simply have a 2.0 full range floorstanders and calibrated to that. One could add calibration points (Placing a mic at various points in a room) to a profile and get amazing results. I did that. It was really good. I still spent time carefully positioning and dialing down the bass manually.
I'm now a convert of many subs in a room

I think 4 is a good starting point

There are things I don't like about it. The screen is too small. The USB receptacle is a mini

It can't digitally do anything above 96/24 although I use it solely as analog in/analog out. The built-in DAC was good enough the optical that it was slightly below my NAD M51 and Oppo BDP105 in performance. For the time being I use the Oppo as a front end and music server.
Having had my eye set on large floorstanders I'm really having to reassess why I need large floor standers when subs now work so well and seem so seamless with whatever monitor I've stuck in my room. I'm thinking 2 of Danny's sealed servo subs might be a good start as the Atoms aren't mine anyway...