Does skin effect produce any sonic discrepancies?
If you're referring to a sleeving that sometimes surrounds the insulated wires apparently it can.
I ordered and received a pair of 16 foot Reality Cables. Prior to ordering I asked my wife if the basic red without sleeving would be OK. She said she would rather me pop for the black sleeving that's optional.
When I placed the order Gregg said that he could hear a difference between the sleeved and unsleeved. No sleeving is better. He also said that the off white cotton sleeving sounds better than the black sleeving. Sorry I don't remember what black sleeving is made of.
I don't know that I would be able to hear the difference but I went with the expert, bought the standard red without sleeving and saved a few bucks.
Here's a link to his site that shows the standard cable and cable with sleeving.
http://www.realitycables.com/products_pricing.html