Yes, I do feel like it is able to handle the NX-Treme's. As with a lot of tube gear, the stated wattage is very deceiving. I even used the PrimaLuna briefly with some Magnepan 1.7i's and it was able to power them reasonably well. On the NX-Treme's it is authoritative. I basically never take the volume past the halfway point, which is quite loud on the NX-Treme's. No sign of the amp ever being strained, clipping, etc.
Still, I have wondered if the extra power from the Evo 400 might take it up a slight notch in the bass regions.
Overall, if you have a chance to try the PrimaLuna I definitely would. They are superbly built, and have the most intoxicating sound of any of the amps I have tried so far (PrimaLuna Evo 300, Doge 10, BHK 250, Benchmark AHB2, Neurochrome Modulus 86 v3, Lyngdorf TDAI-2170).