What's the rest of the setup look like? Is it Polk all around?
The nemesis is a PERFECT match for the other Odyssey speakers with the possible exception of the Lorelei. When I bought my Lors I also picked up a Nemesis. It's a great center, very articulate, clear, handsome and as I said, voiced exactly to the Nightingale, Circe and Epiphony. For me, though, it didn't have enough to keep up with the Lors so I went another direction.
That said, it's going to depend on your other speakers and how they are voiced. The ring radiator tweeter used in the LSiC has a very specific voice to it which is very different from the Nemesis. I would also say the LSiC probably has a little more low end grunt. However, if you're using this mostly for movies and not 5.1 audio then that may be less of an issue. The nemeis was great at dialog.