Got my EE M88 in 2011, only now, June 2014, i changed the smaller tubes.
I had already changed the major kt 88 tubes about a year ago, as I had one stoke gone bad on me, and musicality had improved. And, once again, the sound quality has improved again with this change. I believe that the main improvement is in the mid to lower frequencies, as I can hear stronger more detailed bass in several pieces: Vingt Six (John Abercrombie), Languta (Hugh Masekela), Us and Them (Anne Bisson). Additionally, it seems also the the music is overall fuller (sorry, it is best word I guess)...
