I changed both pairs of op-amps in my Insight pre-amp some time ago, but just now got around to changing those in my Ultra and Insight DACs. This was the sequence:
1 Listen to both DACs with an orchestral and a choral CD.
2 Change op-amps in the Ultra.
3 Repeat 1.
4 Change op-amps in the Insight.
5 Repeat 1.
In step 3, my bionic eared wife couldn't really hear a difference. She could in step 1. of course, she didn't really know which she was listening to in any test (the order of presentation was varied from test to test). During step 5, she thought the difference was again similar to 1, but overall both were "smoother and more detailed". I agreed, except that I could pick out which was which in 1, 3, and 5 (I didn't always remember which was connected). The new chip allows more inner detail to be heard. The difference between DACs is as I described in another post.