Jazz and Baroque,
Under the Geddes placement paradigm, placing one of the low frequency sources closer to the ceiling than the floor is desirable, but it's not like the sound falls apart if you don't. You'd probably still be better off than with symmetrical placement. In fact, the remaining floor-to-ceiling standing wave mode can be addressed by placement of subs in the horizontal plane (I can describe this if you'd like).
JoshK talks about dipole subwoofers having a better power response match-up with dipole main speakers. I used to think the same thing, and indeed this is true if the crossover frequency is high enough. But with a low enough crossover frequency, it's not really applicable. The reason is this: The ear cannot separate the first-arrival from the reverberant energy at low frequencies (this is why resarch has shown the human ear cannot detect the location of a sound source below 80 Hz or so; any subwoofer localization that you hear is due to higher frequencies leaking through). You see, by the time the ear detects a low frequency fundamental, the localization time interval has passed so the ear classifies it as reverberant energy and doesn't hear its direction. Thus at low frequencies it's all "power response", and the radiation pattern shapes don't really enter into the picture. [If radiation pattern shape was a dominant factor at very low frequencies we might expect dipoles to have better "impact" than monopoles due to their higher directivity, but such is not the case.] Fortuntely it's quite simple - when we match the levels, we have matched the power response.
It can be beneficial to operate the subs in a multisub system in some sort of mixed-phase arrangement (front subs out of phase with rear subs, left side out of phase with right side, or in an X-like configuration). The result is not the audible nulling you'd expect, because the power response dominates. Mixed-phase configurations can enhance the sense of spaciousness and envelopment, and further smooth the in-room response.
Rajacat,
Using mixed subwoofers is indeed acceptable. Geddes uses three vented low frequency sources and two sealed ones in his dedicated mutichannel listening room. He uses two vented and one bandpass (vented variation) in his two-channel upstairs living room, or did the last time I was there. He counts his main speakers as low frequency sources; they're about 6 dB down in the mid 30's.
Duke