I'm a believer in Adire's xbl^2 technology. If you haven't heard the speed and depth of the Extremis drivers and the detail provided by the CSS WR125S, you're in for a treat if you build the Apex. I have been extremely happy with my 2641 towers. I can only imagine that the Apex is even better.
If you don't want to take my word for it here's what I'd do:
-- Buy a pair of the midrange drivers for both speakers. Build small sealed boxes for them and evaluate which midrange voice and signature you like better. This signature will likely carry over to the sound coming from the full towers.
Good luck, let us know what you chose.