Seriously doubt it. Keep in mind that the whole-house generator still relies on the same infrastructure, i.e., the wiring inside your walls, etc. That's different from powering your audio system only via a battery-powered generator. I have two EcoFlow units, and I've never hooked up my audio system to hear if it sounds better. If so, every hard-core audiophile would own one. Also, you'll need a pure sine wave generator (many say they are, but aren't), and you'll need to try various types and brands of batteries.