I use Audirivana plus on a Mojo Mac Mini, SDD, external 1TB OWC Mercury Elite pro mini FW800 Audioquest Carbon, Audioquest USB Coffee to Oppo 105 (modified by AudioMagic goodies: Super Fuse, Pulse Gen ZX, Blackout box on transformer and blackout paint on the caps). I run it headless via MacBook Pro. I have used the iPad but find those things more annoying than practical.
I have not experimented with the iTunes interface and Audirivana. I heard that GUI is a sonic compromise and although the album art is nice, it is less of a benefit in the headless config. I am extremely satisfied with the Apple solution. I have also used Pure Music and JRiver (windows). For my purposes, the simplicity and sonic performance of this setup are the best solution. I do think JRiver is a much more capable and excellent software solution for multi-user setup. IMHO