For best sound quality, connecting the computer to the DAC directly, using USB (async) or FireWire is best. Remote control can be done with iPhone or iPad using the various remote control apps that vary by platform (Mac versus PC).
Having said that, if whole house distribution is desired, a convenient, out-of-the-box ready and higher quality alternative to the Airport Express is the Sonos system.
There used to also exist Squeezebox and Bolder cable does mods for them, but Logitech has killed the Squeezebox product line.
Finally, if you want to continue using the Airport Express and just want to eliminate jitter, Empirical Audio has (in my opinion) the very highest quality reclockers. But the BDA-1 could very well have good de-jittering performance, so I'd wait to get the BDA-1 before taking an Empirical Audio Synchro Mesh for a trial.
What are you using now for a DAC? Or are you using the analog out of he Airport Express?