I've been running an unraid NAS for many years (at least 10). I think in that time, I've had two drives (both WD green drives) fail (one at a time). The second one I'm not sure I had to replace, but I wanted more storage. I just shut down the server, replaced the drive, recalculated parity, and I was done. I also should mention that I did replace other drives, as I'm now using a 3TB parity drive, with two 1.5 TB drives and the rest are 2TB drives. I've slowly been getting rid of the 1-1.5TB drives (in fact, when I get time, I have a 2TB drive to replace one of the 1.5TB drives). I currently have 7TB of storage, 3TB of parity, and 2TB of cache/hot spare.
Currently, I'm running 6 disks, of which 4 are western digital green drives and two are seagate.
I also have two 4 TB drives I use for backups. These are both WD green drives. I take one to work, and I run it daily to listen to music. The other, I only run when performing a backup.