What kind of trouble?
Over the past ten years I've had two of the larger active ATC models in the room (50 and 100). Both needed to be out from the wall four feet or so to let the midrange and treble open up, but the bass was best when the speakers were closer to the wall. Out in the room, bass got very uneven. Worse, in my preferred setup on the short wall, certain bass frequencies just went MIA. There's a deep bass note, repeated on every chorus, on a favorite Lyle Lovett track (She's Already Made Up Her Mind) that illustrated the trouble perfectly. On the short wall setup, it felt as if the bass notes were having a fistfight in the middle of the room somehow, and getting canceled out in the process. The was sort of a fuzzy vibration in the air, but no real note.
I had similar problems with the Linkwitz Orions, which in my room also sounded (and measured) very shelved down from the upper midrange on up. I never could get involving sound out of those speakers, which knocked me out whenever I heard them in other rooms. Drums in particular never sounded close to right; the ATC's had done better.
Speakers I've had before this past decade included Meadowlarks (the Kestrel did pretty well) and many other box speakers that all exhibited bass boom and uneven room response. I sometimes think my living room is where speakers come to die...
The room is 14'3" x 21', with an 8' ceiling. There's a front door entrance, and two hallway entrances, plus a direct-vent gas fireplace on the short wall. I think I could place four subs against the walls in this room according to your and Jim's suggested plan. I'm not into tube amps - the closest I get is a hybrid Van Alstine preamp - so no worries about impedance matching, etc.
I photograph a lot of jazz performance. I'm looking for a system that gives a reasonable facsimile of the "jump" one hears from real instruments in small to medium spaces, along with honest timbre. This is my living room, so I'd prefer to avoid a bunch of acoustic treatments if possible. The main speakers can be three to four feet away from all walls if need be. The less they have to be located out into the room, the better.
Any chance you'll be up in Seattle again anytime soon?