If you're going to substitute a positive drive fastener (Hex head, Robertson/Scrulox, etc) keep in mind the torque you apply to the fastener. Positive drive fasteners will allow you to over-torque the assembly. Slotted, JIS, or Phillips head screws are deliberately designed to cam out when you apply too much torque.
The JIS fastener looks broadly like a Phillips head, but is different and you won't be able to apply the correct torque if you use the wrong driver. Few people actually have the JIS drivers in North America but it's worth the investment if you disassemble anything. Even more so that applies to slotted drivers, where there are ... I dunno ... maybe a thousand different drivers ... to fit specific slotted screw sizes. They were still very commonly used in manufactured products in the UK until the Metric System saved us from them (don't ever say the Metric System didn't do anything for America ...). The JIS (Japan Industrial Standard) is often found in electronics, but more consistently in Cameras, laptops, etc.
If you're assembling speakers or cabinets by hand, a very handy thing to have around is a bar of soap (Ivory, etc). Simply drag the last few threads of the screw over the soap bar before you start assembly ... you don't need much so if practically any amount sticks, you're good to go. You can dampen the bar a bit if you want, but dry is OK too. It will significantly reduce the friction and the assembly will tighten up quite nicely. You'll have to insure there's no residue on the head of the screw or the wood if you intend to paint, etc.