To me, the question would be:
Does performing surgery on audio equipment reduce its resale value?
and the general answer would have to be yes, because the general population would rather you just didn't.
Then there is a set of potential buyers who would possibly trust an audiophile who knows what they are doing, who would not feel that this reduced the value in any way.
Then there is a subset of the above set who does not feel good about lead anywhere in their house (do the drivers slowly pump lead dust into baby's lungs..).
There are of course other sets of potential buyers, but basically you have to realize that you will be selling to a particular set of people and excluding others, a situation which probably 99% of audiophiles are in when they sell their gear.
But I see that this is a question more about lead toxicity...
When I visited Pompeii, I learned to my amazement that they had lead pipes running throughout the city into houses and fountains and baths. Did this harm them? The general consensus is no, because a thick coating of mineral deposits formed inside the pipes before there was damage from lead, and alternatively, that something else got to them first (if not a multitude of diseases, then something else such as scorching volcanic ash and boiling mud). Actually many of them did get rescued by sea, and may have gone on to suffer some kind of lead poisoning, but those pipes that I did see had a pretty good layer of white mineral deposits inside them.