I'm assuming you could integrate a powered sub with these speakers.
Absolutely.
I'm as big a fan as there is for the Linkwitz designs, but the LXmini (sans subwoofer) would not do it for me as my everyday system to play all music. I play too much music with bass, loudly.

But, the LXmini system would certainly work for many users, standalone.
Also, you've posted this query in the "open-baffle" section of AC, but just want to make you're clear this is not really an open-baffle system. It's a closed-box omni speaker for much of its frequency range.
Cheers,
Dave.