I cannot directly answer your question because I don't own/haven't even heard CAMs. However, I have had 3 + subwoofer for just over 8 years. The sub is a Rhythmic F12. I have an inexpensive Musical Paradise MP-301 tube amp.
I have questioned whether I should move to other Omega offerings. I'm sure they could sound better (or different, if anything), but part of the magic comes from knowing that I only spent less than $500 and they sound amazing. Easily the best (relative) bargain in all of my audio purchases.
I have removed the sub a few times and tried to convince myself that I could like without it. However, it always makes it's way back into the system.