I think I've exhausted all the options on a BDP-1 (BDP-2 should also be covered).
You can do native Manic Moose MPD (USB drives as media source, or wired NAS as source, wireless NAS as source with USB Wi-fi adapter)
You can do Roon wired (ethernet cable on BDP-1) and wireless (USB Wi-fi adapter on the BDP-1). If you do wireless, make sure no ethernet cable is plugged on the BDPs. I've done a post or two on this before with setup. Also, Chris/Bryston made a very helpful guide as well that should hopefully still be available. You can get their USB Wi-fi adapters, or third party like I did for a much lower price. Mine worked flawlessly and still does in another IPTV rig.
With Roon, all your music must first go through Roon Core, which can only run on desktops/laptops. It doesn't matter whether that music is your own on USB drives and/or streamed music from Tidal/Qobuz. It will all first come to Roon and then out to the Bryston BDP player.
When using Roon, you ideally want the music itself wired to the Roon Core device (laptop/computer). NAS can be used for storage of media for Roon to pull the music off of, but direct storage like USB is preferred. You can also use the USB drives attached to the BDP as a media source for Roon, but that's not recommended. You'll be adding unnecessary load on the network and on BDP. I've done it in the past with mixed results. Not recommended.
Have the USB drives connected to Roon Core (computer) directly for best Roon experience. In my case, my USB music drive was connected to my iMac running Roon Core. I've tried full wireless (both iMac and BDP-1 wireless) and full wired (both iMac and BDP-1 wired) to a local switch/router. If you have decent internet speeds and a decent router in correct locations, it works just as good. I didn't experience any dropouts and it was very responsive with full wireless mode. You couldn't tell the difference in experience as the end user between wired or wireless.
As far as SQ goes, I've written about that many times on all the Roon and MPD comparisons and the many ways to feed them. Wireless USB adapters for both MPD and Roon use, wired and wireless NAS for BDP-1, local USB flash drive vs. portable 2.5" spinning HDD drives, FLAC vs. WAV in MPD out of NAS and various USB drives, Audioquest Jitterbug for USB drives and/or the wireless Wifi adapter connecting to the BDP-1, linear power supplies for the network router/switch, 5 network switch and router (both gigabit and 100 mbps - slow everything to 100 Mbps), direct bridged ethernet connection from the computer to the BDP-1 without any router/switch involved.
There are many options and they all have different SQ. Most people seem to like MPD for SQ over Roon. Within MPD, some people like music off a NAS vs. USB drives from a SQ point alone.
Anyways, try it out and if you run into issues, someone here or on the Roon forum can likely help out. Good luck!