How many subs are you thinking of? (The more the better to minimize +/- 20 dB in-room responses.)
Audio only (sealed recommended), HT only (ported recommended), or both (sealed recommended)?
The Bryston is big (as is your room) and expensive. For the price I'd much rather have 4 well respected servo Rythmik 15" sealed or dual 12" sealed subs for the same price as that Bryston (or less).