I have the MW LS100 and KWA100SE, I don't leave either on 24/7, and switch on the equipment as noted above. That said, to me leaving the LS100 on 24/7 without listening is a needless waste of tube life , just let it warm up 15 -20 minutes before critical listening. I'll also add this, in addition to the MW gear in my main system I rotate in 2 tube integrated amps a Line Magnetic LM 518IA and a Finale Audio 7189 MK2 - each "variant" gets 2 weeks play then I rotate in one of the others ; I don't notice any dropoff in musicality using the equipment in this manner