Every room is unique and should be treated as such…so take all comments (at least mine) with a grain of salt, please.
I like to treat a room for a couple of different things.
First, I like to tame room modes below 500 Hz or so with bass traps, etc. The more the better and I like them thick…12" thick is great!
Second, I like to tame decay so the room gets back to flat sooner (as seen on waterfall graphs). This seems to aid clarity and detail a lot!
Third, I like to have a diffusion on the sides and front corners and absorption on the front and back walls generally speaking. So my sides are live and my front and back are dead, if you will. This is for a medium to large room. I follow the 1' per 1" of diffusion depth rule (so I need to be at least six feet away from a diffusor that is 6" deep, for example). This can change things with a small room (significantly).
I then like to move stuff around and see how things sound. Diffusion here, there, absorption here, there. Just listen to see what sounds right to you.
Finally, I like to treat my corners very much. I cover my corners with bass traps and diffusion and I make sure I have corner triangles in place if my ceiling/wall/wall corner is exposed. I don't like 90 degree intersections in my room (three way 90 degrees being the worst).
Most important: space the OB speaker a lot farther from the front wall than ever before…"tune" them to get a clear image. Think of the front wall reflection as a tuning experiment and move the OB speakers further/closer to the front wall to match the first reflection timing that creates space but not blurry imaging.
Best,
John