I have owned cats for 15+ years, often more than 1 at a time.
I usually get rescues that are around 3-5 years old at the time I adopt them.
I currently have a 5 year old male, and 2 new kittens. And Maggies.
The 5 year old was 1 when we got him (at the time we had a 15 year old male that passed 2 years later) and he has never, ever given a piece of audio equipment a 2nd look.
The 2 new kittens are different. In spite of MANY scratching posts, they have climbed the Maggies on more than 1 occasion. I have a water gun I spray them with when they get caught. The smarter of the 2 new ones picked up on that after 1 event. The more rambunctious caught on after 3 events.
The socks on the Maggies have been mildly damaged (a couple of pulls, no holes, and no damage to the drivers or speaker functionality).
I now leave the kittens locked in the basement overnight. That is where the Maggies live too.
So far so good. I basically decided early on that because we all wanted cats, and only I wanted huge speakers that appear to be large black scratching posts I was going to have to suck it up. I resigned myself to replace the socks in the future should they suffer from the cats.
I would not worry much about mostly wood speakers with grills, unless they start "marking their territory" beyond simply wanting something to stretch on, or climb once or twice.
Now, they could knock speakers off stands, so blu-tack might be critical for stand mounts.