I dont have any omega speakers but i would say the application is pretty similar with any other speakers. If you can integrate them well to your liking in fullrange set up, there is no reason why not run them fullrange. But as always, having them integrate properly is the main issue. And having a bass management can really help, specially when you are limit to location on Sub.
If you have only one sub, i would try running them no higher than 80hz. You should also adjust the distance on your processor or avr.