I'm a bit of a nutjob with three systems. And I've got a wife and two teenage girls, so systems need to integrate into a family lifestyle.
My main living room system is the Classic 30s driven right now by a Margules amp/preamp with a custom Rega RP6/Ortofon 2M Black and an Oppo 105 universal player -- Nordost Red Dawn loom.
My basement system is a bit of a Franken-sys; DIY Pass/Lowther bi-amped system using a Threshold amp for the woofers and a Dennis Had SET for the Lowthers. Front end is a bluetooth receiver and a NAD Master SACD player. Cables are DIY and Acoustic Zen.
I've got a pretty sweeeeet setup in my vacation home/man cave. ASL 845 monoblocks running PureAudioProject Trio15 OB speakers, a 2-box Canary preamp (very sweet), a Pro-ject 10 ttbl with a Soundsmith Aria HO cart, and a PS Audio PerfectWave Transport, PS Audio DAC, and P3 line conditioner. I love this system the most, but it takes up a bit of real estate, and wouldn't fit in my home. Alas!
Great times sharing great music with friends over food and wine any chance I get...