Yes, tubes can hum if they are micro. I can always hear when signal tubes get bad enough, so never experienced a fiery death so to speak. Signal tubes lose focus when they start wearing out, or become noisy or hum. If you are using new production tubes, I would just change them out every couple years or so. Old stock tubes can last a lifetime though, but you will pay for it.
Rectifier tubes can short, open, flash over, etc, but they are typically good and strong until they die. Same for large output tubes.