Both designs have a nice flat SPL response with a slight downward slope. I think the trade-offs are as follows.
FR - W - W : The Lowther is close to ear level for a sitting listener but the vertical radiation pattern is biased down towards the floor. You will probably get significant low frequency reinforcement, and also a few dips, from the floor bounce. I had a similar design on my room many years ago and it performed quite well.
W - FR - W : the vertical radiation pattern is much more uniform. But the Lowther is well below a sitting ear level hence the slanting back of the OB in the simulation.
In both designs the L-Pad can be tweaked to adjust the SPL output from the Lowther to produce the best results in a given room. If I was picking between one or the other I would probably use the second option and build an adjustable base for the OB so I could vary the angle of tilt. I would make sure I was sitting on axis for the Lowther and then adjust the toe in a little so I was slightly to the side of this axis.